FOXA1 mutations influence the therapeutic response of breast cancer by altering chromatin state

di Arruabarrena-Aristorena, Amaia, Toska, Eneda
Pubblicato in Mol Cell Oncol (2021)

Oil for the cancer engine: The cross-talk between oncogenic signaling and polyamine metabolism

di Arruabarrena-Aristorena, Amaia, Zabala-Letona, Amaia, Carracedo, Arkaitz
Pubblicato in Sci Adv (2018)

HEY1 functions are regulated by its phosphorylation at Ser-68

di López-Mateo, Irene, Arruabarrena-Aristorena, Amaia, Artaza-Irigaray, Cristina, López, Juan A., Calvo, Enrique, Belandia, Borja
Pubblicato in Biosci Rep (2016)

PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression

di Toska, Eneda, Castel, Pau, Chhangawala, Sagar, Arruabarrena-Aristorena, Amaia, Chan, Carmen, Hristidis, Vasilis C., Cocco, Emiliano, Sallaku, Mirna, Xu, Guotai, Park, Jane, Minuesa, Gerard, Shifman, Sophie G., Socci, Nicholas D., Koche, Richard, Leslie, Christina S., Scaltriti, Maurizio, Baselga, José
Pubblicato in Cell Rep (2019)

PTEN mediates Notch-dependent stalk cell arrest in angiogenesis

di Serra, Helena, Chivite, Iñigo, Angulo-Urarte, Ana, Soler, Adriana, Sutherland, James D., Arruabarrena-Aristorena, Amaia, Ragab, Anan, Lim, Radiance, Malumbres, Marcos, Fruttiger, Marcus, Potente, Michael, Serrano, Manuel, Fabra, Àngels, Viñals, Francesc, Casanovas, Oriol, Pandolfi, Pier Paolo, Bigas, Anna, Carracedo, Arkaitz, Gerhardt, Holger, Graupera, Mariona
Pubblicato in Nat Commun (2015)

Low-dose statin treatment increases prostate cancer aggressiveness

di Caro-Maldonado, Alfredo, Camacho, Laura, Zabala-Letona, Amaia, Torrano, Verónica, Fernández-Ruiz, Sonia, Zamacola-Bascaran, Kepa, Arreal, Leire, Valcárcel-Jiménez, Lorea, Martín-Martín, Natalia, Flores, Juana M., Cortazar, Ana R., Zúñiga-García, Patricia, Arruabarrena-Aristorena, Amaia, Guillaumond, Fabienne, Cabrera, Diana, Falcón-Perez, Juan M., Aransay, Ana M., Gomez-Muñoz, Antonio, Olivan, Mireia, Morote, Juan, Carracedo, Arkaitz
Pubblicato in Oncotarget (2017)

Targeting PML in triple negative breast cancer elicits growth suppression and senescence

di Arreal, Leire, Piva, Marco, Fernández, Sonia, Revandkar, Ajinkya, Schaub- Clerigué, Ariane, Villanueva, Josep, Zabala-Letona, Amaia, Pujana, Mikel, Astobiza, Ianire, Cortazar, Ana Rosa, Hermanova, Ivana, Bozal-Basterra, Laura, Arruabarrena-Aristorena, Amaia, Crespo, Jana R., Valcarcel-Jimenez, Lorea, Zúñiga-García, Patricia, Canals, Francesc, Torrano, Veronica, Barrio, Rosa, Sutherland, James D., Alimonti, Andrea, Martin-Martin, Natalia, Carracedo, Arkaitz
Pubblicato in Cell Death Differ (2019)

FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer

di Arruabarrena-Aristorena, Amaia, Maag, Jesper L.V., Kittane, Srushti, Cai, Yanyan, Karthaus, Wouter R., Ladewig, Erik, Park, Jane, Kannan, Srinivasaraghavan, Ferrando, Lorenzo, Cocco, Emiliano, Ho, Sik Y., Tan, Daisylyn S., Sallaku, Mirna, Wu, Fan, Acevedo, Barbara, Selenica, Pier, Ross, Dara S., Witkin, Matthew, Sawyers, Charles L., Reis-Filho, Jorge S., Verma, Chandra S., Jauch, Ralf, Koche, Richard, Baselga, José, Razavi, Pedram, Toska, Eneda, Scaltriti, Maurizio
Pubblicato in Cancer Cell (2020)

Transcriptomic profiling of urine extracellular vesicles reveals alterations of CDH3 in prostate cancer

di Royo, Felix, Zuñiga-Garcia, Patricia, Torrano, Verónica, Loizaga, Ana, Sanchez-Mosquera, Pilar, Ugalde-Olano, Aitziber, González, Esperanza, Cortazar, Ana R., Palomo, Laura, Fernández-Ruiz, Sonia, Lacasa-Viscasillas, Isabel, Berdasco, Maria, Sutherland, James D., Barrio, Rosa, Zabala-Letona, Amaia, Martín-Martín, Natalia, Arruabarrena-Aristorena, Amaia, Valcarcel-Jimenez, Lorea, Caro-Maldonado, Alfredo, Gonzalez-Tampan, Jorge, Cachi-Fuentes, Guido, Esteller, Manel, Aransay, Ana M., Unda, Miguel, Falcón-Pérez, Juan M., Carracedo, Arkaitz
Pubblicato in Oncotarget (2016)

TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors

di Cocco, Emiliano, Lee, Ji Eun, Kannan, Srinivasaraghavan, Schram, Alison M, Won, Helen H, Shifman, Sophie, Kulick, Amanda, Baldino, Laura, Toska, Eneda, Arruabarrena-Aristorena, Amaia, Kittane, Srushti, Wu, Fan, Cai, Yanyan, Arena, Sabrina, Mussolin, Benedetta, Kannan, Ram, Vasan, Neil, Gorelick, Alexander N., Berger, Michael F, Novoplansky, Ofra, Jagadeeshan, Sankar, Liao, Yi, Rix, Uwe, Misale, Sandra, Taylor, Barry S, Bardelli, Alberto, Hechtman, Jaclyn F, Hyman, David M, Elkabets, Moshe, de Stanchina, Elisa, Verma, Chandra S, Ventura, Andrea, Drilon, Alexander, Scaltriti, Maurizio
Pubblicato in Cancer Discov (2020)

The metabolic co-regulator PGC1α suppresses prostate cancer metastasis

di Torrano, Veronica, Valcarcel-Jimenez, Lorea, Cortazar, Ana Rosa, Liu, Xiaojing, Urosevic, Jelena, Castillo-Martin, Mireia, Fernández-Ruiz, Sonia, Morciano, Giampaolo, Caro-Maldonado, Alfredo, Guiu, Marc, Zúñiga-García, Patricia, Graupera, Mariona, Bellmunt, Anna, Pandya, Pahini, Lorente, Mar, Martín-Martín, Natalia, Sutherland, James David, Sanchez-Mosquera, Pilar, Bozal-Basterra, Laura, Zabala-Letona, Amaia, Arruabarrena-Aristorena, Amaia, Berenguer, Antonio, Embade, Nieves, Ugalde-Olano, Aitziber, Lacasa-Viscasillas, Isabel, Loizaga-Iriarte, Ana, Unda-Urzaiz, Miguel, Schultz, Nikolaus, Aransay, Ana Maria, Sanz-Moreno, Victoria, Barrio, Rosa, Velasco, Guillermo, Pinton, Paolo, Cordon-Cardo, Carlos, Locasale, Jason W., Gomis, Roger R., Carracedo, Arkaitz
Pubblicato in Nat Cell Biol (2016)

Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer

di Hermanova, Ivana, Zúñiga-García, Patricia, Caro-Maldonado, Alfredo, Fernandez-Ruiz, Sonia, Salvador, Fernando, Martín-Martín, Natalia, Zabala-Letona, Amaia, Nuñez-Olle, Marc, Torrano, Verónica, Camacho, Laura, Lizcano, Jose M., Talamillo, Ana, Carreira, Suzanne, Gurel, Bora, Cortazar, Ana R., Guiu, Marc, López, Jose I., Martinez-Romero, Anabel, Astobiza, Ianire, Valcarcel-Jimenez, Lorea, Lorente, Mar, Arruabarrena-Aristorena, Amaia, Velasco, Guillermo, Gomez-Muñoz, Antonio, Suárez-Cabrera, Cristian, Lodewijk, Iris, Flores, Juana M., Sutherland, James D., Barrio, Rosa, de Bono, Johann S., Paramio, Jesús M., Trka, Jan, Graupera, Mariona, Gomis, Roger R., Carracedo, Arkaitz
Pubblicato in J Exp Med (2020)

Methodological aspects of the molecular and histological study of prostate cancer: Focus on PTEN

di Ugalde-Olano, Aitziber, Egia, Ainara, Fernández-Ruiz, Sonia, Loizaga-Iriarte, Ana, Zuñiga-García, Patricia, Garcia, Stephane, Royo, Félix, Lacasa-Viscasillas, Isabel, Castro, Erika, Cortazar, Ana R., Zabala-Letona, Amaia, Martín-Martín, Natalia, Arruabarrena-Aristorena, Amaia, Torrano-Moya, Verónica, Valcárcel-Jiménez, Lorea, Sánchez-Mosquera, Pilar, Caro-Maldonado, Alfredo, González-Tampan, Jorge, Cachi-Fuentes, Guido, Bilbao, Elena, Montero, Rocío, Fernández, Sara, Arrieta, Edurne, Zorroza, Kerman, Castillo-Martín, Mireia, Serra, Violeta, Salazar, Eider, Macías-Cámara, Nuria, Tabernero, Jose, Baselga, Jose, Cordón-Cardo, Carlos, Aransay, Ana M., Villar, Amaia Del, Iovanna, Juan L., Falcón-Pérez, Juan M., Unda, Miguel, Bilbao, Roberto, Carracedo, Arkaitz
Pubblicato in Methods (2015)

Stratification and therapeutic potential of PML in metastatic breast cancer

di Martín-Martín, Natalia, Piva, Marco, Urosevic, Jelena, Aldaz, Paula, Sutherland, James D., Fernández-Ruiz, Sonia, Arreal, Leire, Torrano, Verónica, Cortazar, Ana R., Planet, Evarist, Guiu, Marc, Radosevic-Robin, Nina, Garcia, Stephane, Macías, Iratxe, Salvador, Fernando, Domenici, Giacomo, Rueda, Oscar M., Zabala-Letona, Amaia, Arruabarrena-Aristorena, Amaia, Zúñiga-García, Patricia, Caro-Maldonado, Alfredo, Valcárcel-Jiménez, Lorea, Sánchez-Mosquera, Pilar, Varela-Rey, Marta, Martínez-Chantar, Maria Luz, Anguita, Juan, Ibrahim, Yasir H., Scaltriti, Maurizio, Lawrie, Charles H., Aransay, Ana M., Iovanna, Juan L., Baselga, Jose, Caldas, Carlos, Barrio, Rosa, Serra, Violeta, dM Vivanco, Maria, Matheu, Ander, Gomis, Roger R., Carracedo, Arkaitz
Pubblicato in Nat Commun (2016)

mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

di Zabala-Letona, Amaia, Arruabarrena-Aristorena, Amaia, Martín-Martín, Natalia, Fernandez-Ruiz, Sonia, Sutherland, James D., Clasquin, Michelle, Tomas-Cortazar, Julen, Jimenez, Jose, Torres, Ines, Quang, Phong, Ximenez-Embun, Pilar, Bago, Ruzica, Ugalde-Olano, Aitziber, Loizaga-Iriarte, Ana, Lacasa-Viscasillas, Isabel, Unda, Miguel, Torrano, Verónica, Cabrera, Diana, van Liempd, Sebastiaan M., Cendon, Ylenia, Castro, Elena, Murray, Stuart, Revandkar, Ajinkya, Alimonti, Andrea, Zhang, Yinan, Barnett, Amelia, Lein, Gina, Pirman, David, Cortazar, Ana R., Arreal, Leire, Prudkin, Ludmila, Astobiza, Ianire, Valcarcel-Jimenez, Lorea, Zuñiga-García, Patricia, Fernandez-Dominguez, Itziar, Piva, Marco, Caro-Maldonado, Alfredo, Sánchez-Mosquera, Pilar, Castillo-Martín, Mireia, Serra, Violeta, Beraza, Naiara, Gentilella, Antonio, Thomas, George, Azkargorta, Mikel, Elortza, Felix, Farràs, Rosa, Olmos, David, Efeyan, Alejo, Anguita, Juan, Muñoz, Javier, Falcón-Pérez, Juan M., Barrio, Rosa, Macarulla, Teresa, Mato, Jose M., Martinez-Chantar, Maria L., Cordon-Cardo, Carlos, Aransay, Ana M., Marks, Kevin, Baselga, José, Tabernero, Josep, Nuciforo, Paolo, Manning, Brendan D., Marjon, Katya, Carracedo, Arkaitz
Pubblicato in Nature (2017)