Cancer-associated chromosomal deletions: Size makes a difference

od Cai, Yanyan, Sablina, Anna A.
Wydane w Cell Cycle (2016)

Phase and context shape the function of composite oncogenic mutations

od Gorelick, Alexander N., Sánchez-Rivera, Francisco J., Cai, Yanyan, Bielski, Craig M., Biederstedt, Evan, Jonsson, Philip, Richards, Allison L., Vasan, Neil, Penson, Alexander V., Friedman, Noah D., Ho, Yu-Jui, Baslan, Timour, Bandlamudi, Chaitanya, Scaltriti, Maurizio, Schultz, Nikolaus, Lowe, Scott W., Reznik, Ed, Taylor, Barry S.
Wydane w Nature (2020)

Genomic alterations in PIK3CA-mutated breast cancer result in mTORC1 activation and limit the sensitivity to PI3Kα inhibitors

od Cai, Yanyan, Xu, Guotai, Wu, Fan, Michelini, Flavia, Chan, Carmen, Qu, Xuan, Selenica, Pier, Ladewig, Erik, Castel, Pau, Cheng, Yuanming, Zhao, Alison, Jhaveri, Komal, Toska, Eneda, Jimenez, Marta, Jacquet, Alexandra, Tran-Dien, Alicia, Andre, Fabrice, Chandarlapaty, Sarat, Reis-Filho, Jorge S., Razavi, Pedram, Scaltriti, Maurizio
Wydane w Cancer Res (2021)

FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer

od Arruabarrena-Aristorena, Amaia, Maag, Jesper L.V., Kittane, Srushti, Cai, Yanyan, Karthaus, Wouter R., Ladewig, Erik, Park, Jane, Kannan, Srinivasaraghavan, Ferrando, Lorenzo, Cocco, Emiliano, Ho, Sik Y., Tan, Daisylyn S., Sallaku, Mirna, Wu, Fan, Acevedo, Barbara, Selenica, Pier, Ross, Dara S., Witkin, Matthew, Sawyers, Charles L., Reis-Filho, Jorge S., Verma, Chandra S., Jauch, Ralf, Koche, Richard, Baselga, José, Razavi, Pedram, Toska, Eneda, Scaltriti, Maurizio
Wydane w Cancer Cell (2020)

Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2)

od Cocco, Emiliano, Carmona, F. Javier, Razavi, Pedram, Won, Helen H., Cai, Yanyan, Rossi, Valentina, Chan, Carmen, Cownie, James, Soong, Joanne, Toska, Eneda, Shifman, Sophie G, Sarotto, Ivana, Savas, Peter, Wick, Michael J., Papadopoulos, Kyriakos P., Moriarty, Alyssa, Cutler, Richard E., Avogadri-Connors, Francesca, Lalani, Alshad S., Bryce, Richard P., Chandarlapaty, Sarat, Hyman, David M., Solit, David B., Boni, Valentina, Loi, Sherene, Baselga, José, Berger, Michael F., Montemurro, Filippo, Scaltriti, Maurizio
Wydane w Sci Signal (2018)

ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer

od Xu, Guotai, Chhangawala, Sagar, Cocco, Emiliano, Razavi, Pedram, Cai, Yanyan, Otto, Jordan E, Ferrando, Lorenzo, Selenica, Pier, Ladewig, Erik, Chan, Carmen, Da Cruz Paula, Arnaud, Witkin, Matthew, Cheng, Yuanming, Park, Jane, Serna-Tamayo, Cristian, Zhao, HuiYong, Wu, Fan, Sallaku, Mirna, Qu, Xuan, Zhao, Alison, Collings, Clayton K, D’Avino, Andrew R., Jhaveri, Komal, Koche, Richard, Levine, Ross L., Reis-Filho, Jorge S., Kadoch, Cigall, Scaltriti, Maurizio, Leslie, Christina S., Baselga, José, Toska, Eneda
Wydane w Nat Genet (2020)

TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors

od Cocco, Emiliano, Lee, Ji Eun, Kannan, Srinivasaraghavan, Schram, Alison M, Won, Helen H, Shifman, Sophie, Kulick, Amanda, Baldino, Laura, Toska, Eneda, Arruabarrena-Aristorena, Amaia, Kittane, Srushti, Wu, Fan, Cai, Yanyan, Arena, Sabrina, Mussolin, Benedetta, Kannan, Ram, Vasan, Neil, Gorelick, Alexander N., Berger, Michael F, Novoplansky, Ofra, Jagadeeshan, Sankar, Liao, Yi, Rix, Uwe, Misale, Sandra, Taylor, Barry S, Bardelli, Alberto, Hechtman, Jaclyn F, Hyman, David M, Elkabets, Moshe, de Stanchina, Elisa, Verma, Chandra S, Ventura, Andrea, Drilon, Alexander, Scaltriti, Maurizio
Wydane w Cancer Discov (2020)

The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers

od Razavi, Pedram, Chang, Matthew T., Xu, Guotai, Bandlamudi, Chaitanya, Ross, Dara S., Vasan, Neil, Cai, Yanyan, Bielski, Craig M., Donoghue, Mark T.A., Jonsson, Philip, Penson, Alexander, Shen, Ronglai, Pareja, Fresia, Kundra, Ritika, Middha, Sumit, Cheng, Michael L., Zehir, Ahmet, Kandoth, Cyriac, Patel, Ruchi, Huberman, Kety, Smyth, Lillian M., Jhaveri, Komal, Modi, Shanu, Traina, Tiffany A., Dang, Chau, Zhang, Wen, Weigelt, Britta, Li, Bob T., Ladanyi, Marc, Hyman, David M., Schultz, Nikolaus, Robson, Mark E., Hudis, Clifford, Brogi, Edi, Viale, Agnes, Norton, Larry, Dickler, Maura N., Berger, Michael F., Iacobuzio-Donahue, Christine A., Chandarlapaty, Sarat, Scaltriti, Maurizio, Reis-Filho, Jorge S., Solit, David B., Taylor, Barry S., Baselga, José
Wydane w Cancer Cell (2018)

Efficacy and Determinants of Response to HER Kinase Inhibition in HER2-Mutant Metastatic Breast Cancer

od Smyth, Lillian M., Piha-Paul, Sarina A., Won, Helen, Schram, Alison M., Saura, Cristina, Loi, Sherene, Lu, Janice, Shapiro, Geoffrey I., Juric, Dejan, Mayer, Ingrid A., Arteaga, Carlos L., de la Fuente, Macarena I., Brufksy, Adam M., Spanggaard, Iben, Mau-Sørensen, Morten, Arnedos, Monica, Moreno, Victor, Boni, Valentina, Sohn, Joohyuk, Schwartzberg, Lee S., Gonzàlez-Farré, Xavier, Cervantes, Andrés, Bidard, François-Clement, Gorelick, Alexander N., Lanman, Richard B., Nagy, Rebecca J., Ulaner, Gary A., Chandarlapaty, Sarat, Jhaveri, Komal, Gavrila, Elena I., Zimel, Catherine, Selcuklu, S. Duygu, Melcer, Myra, Samoila, Aliaksandra, Cai, Yanyan, Scaltriti, Maurizio, Mann, Grace, Xu, Feng, Eli, Lisa D., Dujka, Melanie, Lalani, Alshad S., Bryce, Richard, Baselga, José, Taylor, Barry S., Solit, David B., Meric-Bernstam, Funda, Hyman, David M.
Wydane w Cancer Discov (2019)

HER2-mediated internalization of cytotoxic agents in ERBB2 amplified or mutant lung cancers

od Li, Bob T., Michelini, Flavia, Misale, Sandra, Cocco, Emiliano, Baldino, Laura, Cai, Yanyan, Shifman, Sophie, Tu, Hai-Yan, Myers, Mackenzie L., Xu, Chongrui, Mattar, Marissa, Khodos, Inna, Little, Megan, Qeriqi, Besnik, Weitsman, Gregory, Wilhem, Clare J., Lalani, Alshad S., Diala, Irmina, Freedman, Rachel A., Lin, Nancy U., Solit, David B., Berger, Michael F., Barber, Paul R., Ng, Tony, Offin, Michael, Isbell, James M., Jones, David R., Yu, Helena A., Thyparambil, Sheeno, Liao, Wei-Li, Bhalkikar, Anuja, Cecchi, Fabiola, Hyman, David M., Lewis, Jason S., Buonocore, Darren J., Ho, Alan L., Makker, Vicky, Reis-Filho, Jorge S., Razavi, Pedram, Arcila, Maria E., Kris, Mark G., Poirier, John T., Shen, Ronglai, Tsurutani, Junji, Ulaner, Gary A., de Stanchina, Elisa, Rosen, Neal, Rudin, Charles M., Scaltriti, Maurizio
Wydane w Cancer Discov (2020)