The expanding landscape of ‘oncohistone’ mutations in human cancers

по Nacev, Benjamin A., Feng, Lijuan, Bagert, John D., Lemiesz, Agata E., Gao, JianJiong, Soshnev, Alexey, Kundra, Ritika, Schultz, Nikolaus, Muir, Tom W., Allis, C. David
Опубликовано в: Nature (2019)

FOLFCIS Treatment and Genomic Correlates of Response in Advanced Anal Squamous Cell Cancer

по Mondaca, Sebastian, Chatila, Walid K., Bates, David, Hechtman, Jaclyn F., Cercek, Andrea, Segal, Neil H., Stadler, Zsofia K., Varghese, Anna M., Kundra, Ritika, Capanu, Marinela, Shia, Jinru, Schultz, Nikolaus, Saltz, Leonard, Yaeger, Rona
Опубликовано в: Clin Colorectal Cancer (2018)

TRK Fusions are Enriched in Cancers with Uncommon Histologies and the Absence of Canonical Driver Mutations

по Rosen, Ezra Y., Goldman, Debra A., Hechtman, Jaclyn F., Benayed, Ryma, Schram, Alison M, Cocco, Emiliano, Shifman, Sophie, Gong, Yixiao, Kundra, Ritika, Solomon, James P., Bardelli, Alberto, Scaltriti, Maurizio, Drilon, Alexander, Iasonos, Alexia, Taylor, Barry S., Hyman, David M.
Опубликовано в: Clin Cancer Res (2019)

Linked Entity Attribute Pair (LEAP): A Harmonization Framework for Data Pooling

по Thomas, Stacy, Lichtenberg, Tara, Dang, Kristen, Fitzsimons, Michael, Grossman, Robert L., Kundra, Ritika, Lavery, Jessica A., Lenoue-Newton, Michele L., Panageas, Katherine S., Sawyers, Charles, Schultz, Nikolaus D., Sirintrapun, Sahussapont J., Topaloglu, Umit, Welch, Angelica, Yu, Thomas, Zehir, Ahmet, Gardos, Stuart
Опубликовано в: JCO Clin Cancer Inform (2020)

Clinical and molecular predictors of response to immune checkpoint inhibitors in patients with advanced esophagogastric cancer

по Greally, Megan, Chou, Joanne F., Chatila, Walid K., Margolis, Matthew, Capanu, Marinela, Hechtman, Jaclyn F., Tuvy, Yaelle, Kundra, Ritika, Daian, Foysal, Ladanyi, Marc, Kelsen, David P., Ilson, David H., Berger, Michael F., Tang, Laura H., Solit, David B., Diaz, Luis A., Schultz, Nikolaus, Janjigian, Yelena Y., Ku, Geoffrey Y.
Опубликовано в: Clin Cancer Res (2019)

Intrahepatic Cholangiocarcinoma with Lymph Node Metastasis: Treatment-Related Outcomes and the Role of Tumor Genomics in Patient Selection

по Jolissaint, Joshua S., Soares, Kevin C., Seier, Kenneth P., Kundra, Ritika, Gönen, Mithat, Shin, Paul J., Boerner, Thomas, Sigel, Carlie, Madupuri, Ramyasree, Vakiani, Efsevia, Cercek, Andrea, Harding, James J., Kemeny, Nancy E., Connell, Louise C., Balachandran, Vinod P., D’Angelica, Michael I., Drebin, Jeffrey A., Kingham, T. Peter, Wei, Alice C., Jarnagin, William R.
Опубликовано в: Clin Cancer Res (2021)

Small cell carcinomas of the bladder and lung are characterized by a convergent but distinct pathogenesis

по Chang, Matthew T., Penson, Alexander, Desai, Neil B., Socci, Nicholas D., Shen, Ronglai, Seshan, Venkatraman E., Kundra, Ritika, Abeshouse, Adam, Viale, Agnes, Cha, Eugene K., Hao, Xueli, Reuter, Victor E., Rudin, Charles M., Bochner, Bernard H., Rosenberg, Jonathan E., Bajorin, Dean F., Schultz, Nikolaus, Berger, Michael F., Iyer, Gopa, Solit, David B., Al-Ahmadie, Hikmat, Taylor, Barry S.
Опубликовано в: Clin Cancer Res (2017)

Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next-Generation Sequencing for Matching Patients to Targeted and Immune Therapies

по Harding, James J., Nandakumar, Subhiksha, Armenia, Joshua, Khalil, Danny N., Albano, Melanie, Ly, Michele, Shia, Jinru, Hechtman, Jaclyn F., Kundra, Ritika, Dika, Imane El, Do, Richard K., Sun, Yichao, Kingham, T. Peter, D’Angelica, Michael I., Berger, Michael F., Hyman, David M., Jarnagin, William, Klimstra, David S, Janjigian, Yelena Y., Solit, David B., Schultz, Nikolaus, Abou-Alfa, Ghassan K.
Опубликовано в: Clin Cancer Res (2018)

Regional Differences in Gallbladder Cancer Pathogenesis: Insights From a Multi-Institutional Comparison of Tumor Mutations

по Narayan, Raja R., Creasy, John M., Goldman, Debra A., Gönen, Mithat, Kandoth, Cyriac, Kundra, Ritika, Solit, David B., Askan, Gokce, Klimstra, David S., Basturk, Olca, Allen, Peter J., Balachandran, Vinod P., D’Angelica, Michael I., DeMatteo, Ronald P., Drebin, Jeffrey A., Kingham, T. Peter, Simpson, Amber L., Abou-Alfa, Ghassan K., Harding, James J., O’Reilly, Eileen M., Butte, Jean M., Matsuyama, Ryusei, Endo, Itaru, Jarnagin, William R.
Опубликовано в: Cancer (2018)

Clinical sequencing defines the genomic landscape of metastatic colorectal cancer

по Yaeger, Rona, Chatila, Walid K., Lipsyc, Marla D., Hechtman, Jaclyn F., Cercek, Andrea, Sanchez-Vega, Francisco, Jayakumaran, Gowtham, Middha, Sumit, Zehir, Ahmet, Donoghue, Mark T.A., You, Daoqi, Viale, Agnes, Kemeny, Nancy, Segal, Neil H., Stadler, Zsofia K., Varghese, Anna M., Kundra, Ritika, Gao, Jianjiong, Syed, Aijazuddin, Hyman, David M., Vakiani, Efsevia, Rosen, Neal, Taylor, Barry S., Ladanyi, Marc, Berger, Michael F., Solit, David B., Shia, Jinru, Saltz, Leonard, Schultz, Nikolaus
Опубликовано в: Cancer Cell (2018)

Genetic Determinants of Cisplatin Resistance in Patients With Advanced Germ Cell Tumors

по Bagrodia, Aditya, Lee, Byron H., Lee, William, Cha, Eugene K., Sfakianos, John P., Iyer, Gopa, Pietzak, Eugene J., Gao, Sizhi Paul, Zabor, Emily C., Ostrovnaya, Irina, Kaffenberger, Samuel D., Syed, Aijazuddin, Arcila, Maria E., Chaganti, Raju S., Kundra, Ritika, Eng, Jana, Hreiki, Joseph, Vacic, Vladimir, Arora, Kanika, Oschwald, Dayna M., Berger, Michael F., Bajorin, Dean F., Bains, Manjit S., Schultz, Nikolaus, Reuter, Victor E., Sheinfeld, Joel, Bosl, George J., Al-Ahmadie, Hikmat A., Solit, David B., Feldman, Darren R.
Опубликовано в: J Clin Oncol (2016)

Accelerating discovery of functional mutant alleles in cancer

по Chang, Matthew T., Bhattarai, Tripti Shrestha, Schram, Alison M., Bielski, Craig M., Donoghue, Mark T.A., Jonsson, Philip, Chakravarty, Debyani, Phillips, Sarah, Kandoth, Cyriac, Penson, Alexander, Gorelick, Alexander, Shamu, Tambudzai, Patel, Swati, Harris, Christopher, Gao, JianJiong, Sumer, Selcuk Onur, Kundra, Ritika, Razavi, Pedram, Li, Bob T., Reales, Dalicia N., Socci, Nicholas D., Jayakumaran, Gowtham, Zehir, Ahmet, Benayed, Ryma, Arcila, Maria E, Chandarlapaty, Sarat, Ladanyi, Marc, Schultz, Nikolaus, Baselga, Jose, Berger, Michael F., Rosen, Neal, Solit, David B., Hyman, David M., Taylor, Barry S.
Опубликовано в: Cancer Discov (2017)

Characteristics and outcome of AKT1 E17K-mutant breast cancer defined through AACR Project GENIE, a clinicogenomic registry

по Smyth, Lillian M., Zhou, Qin, Nguyen, Bastien, Yu, Celeste, Lepisto, Eva M., Arnedos, Monica, Hasset, Michael J., Lenoue-Newton, Michele L., Blauvelt, Natalie, Dogan, Semih, Micheel, Christine M., Wathoo, Chetna, Horlings, Hugo, Hudecek, Jan, Gross, Benjamin E., Kundra, Ritika, Sweeney, Shawn M., Gao, JianJiong, Schultz, Nikolaus, Zarski, Andrew, Gardos, Stuart M., Lee, Jocelyn, Sheffler-Collins, Seth, Park, Ben H., Sawyers, Charles L., Andre, Fabrice, Levy, Mia, Meric-Bernstam, Funda, Bedard, Philippe L., Iasonos, Alexia, Schrag, Deborah, Hyman, David M.
Опубликовано в: Cancer Discov (2020)

Prospective comprehensive molecular characterization of lung adenocarcinomas for efficient patient matching to approved and emerging therapies

по Jordan, Emmet J., Kim, Hyunjae R., Arcila, Maria E., Barron, David, Chakravarty, Debyani, Gao, JianJiong, Chang, Matthew T., Ni, Andy, Kundra, Ritika, Jonsson, Philip, Jayakumaran, Gowtham, Gao, Sizhi Paul, Johnsen, Hannah C., Hanrahan, Aphrothiti J., Zehir, Ahmet, Rekhtman, Natasha, Ginsberg, Michelle S., Li, Bob T., Yu, Helena A., Paik, Paul K., Drilon, Alexander, Hellmann, Matthew D., Reales, Dalicia N., Benayed, Ryma, Rusch, Valerie W., Kris, Mark G., Chaft, Jamie E., Baselga, Jose, Taylor, Barry S., Schultz, Nikolaus, Rudin, Charles M., Hyman, David M., Berger, Michael F., Solit, David B., Ladanyi, Marc, Riely, Gregory J.
Опубликовано в: Cancer Discov (2017)

Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making

по Abida, Wassim, Armenia, Joshua, Gopalan, Anuradha, Brennan, Ryan, Walsh, Michael, Barron, David, Danila, Daniel, Rathkopf, Dana, Morris, Michael, Slovin, Susan, McLaughlin, Brigit, Curtis, Kristen, Hyman, David M., Durack, Jeremy C., Solomon, Stephen B., Arcila, Maria E., Zehir, Ahmet, Syed, Aijazuddin, Gao, Jianjiong, Chakravarty, Debyani, Vargas, Hebert Alberto, Robson, Mark E., Vijai, Joseph, Offit, Kenneth, Donoghue, Mark T.A., Abeshouse, Adam A., Kundra, Ritika, Heins, Zachary J., Penson, Alexander V., Harris, Christopher, Taylor, Barry S., Ladanyi, Marc, Mandelker, Diana, Zhang, Liying, Reuter, Victor E., Kantoff, Philip W., Solit, David B., Berger, Michael F., Sawyers, Charles L., Schultz, Nikolaus, Scher, Howard I.
Опубликовано в: JCO Precis Oncol (2017)

Genetic predictors of response to systemic therapy in esophagogastric cancer

по Janjigian, Yelena Y., Sanchez-Vega, Francisco, Jonsson, Philip, Chatila, Walid K., Hechtman, Jaclyn F., Ku, Geoffrey Y., Riches, Jamie C., Tuvy, Yaelle, Kundra, Ritika, Bouvier, Nancy, Vakiani, Efsevia, Gao, Jianjiong, Heins, Zachary J., Gross, Benjamin E., Kelsen, David P., Zhang, Liying, Strong, Vivian E., Schattner, Mark, Gerdes, Hans, Coit, Daniel G., Bains, Manjit, Stadler, Zsofia K., Rusch, Valerie W., Jones, David R., Molena, Daniela, Shia, Jinru, Robson, Mark E., Capanu, Marinela, Middha, Sumit, Zehir, Ahmet, Hyman, David M., Scaltriti, Maurizio, Ladanyi, Marc, Rosen, Neal, Ilson, David H., Berger, Michael F., Tang, Laura, Taylor, Barry S., Solit, David B., Schultz, Nikolaus
Опубликовано в: Cancer Discov (2017)

The long tail of oncogenic drivers in prostate cancer

по Armenia, Joshua, Wankowicz, Stephanie A.M., Liu, David, Gao, Jianjiong, Kundra, Ritika, Reznik, Ed, Chatila, Walid K., Chakravarty, Debyani, Han, G. Celine, Coleman, Ilsa, Montgomery, Bruce, Pritchard, Colin, Morrissey, Colm, Barbieri, Christopher E., Beltran, Himisha, Sboner, Andrea, Zafeiriou, Zafeiris, Miranda, Susana, Bielski, Craig M., Penson, Alexander V., Tolonen, Charlotte, Huang, Franklin W., Robinson, Dan, Wu, Yi Mi, Lonigro, Robert, Garraway, Levi A., Demichelis, Francesca, Kantoff, Philip W., Taplin, Mary-Ellen, Abida, Wassim, Taylor, Barry S., Scher, Howard I., Nelson, Peter S., de Bono, Johann S., Rubin, Mark A., Sawyers, Charles L., Chinnaiyan, Arul M., Schultz, Nikolaus, Van Allen, Eliezer M.
Опубликовано в: Nat Genet (2018)

The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers

по Razavi, Pedram, Chang, Matthew T., Xu, Guotai, Bandlamudi, Chaitanya, Ross, Dara S., Vasan, Neil, Cai, Yanyan, Bielski, Craig M., Donoghue, Mark T.A., Jonsson, Philip, Penson, Alexander, Shen, Ronglai, Pareja, Fresia, Kundra, Ritika, Middha, Sumit, Cheng, Michael L., Zehir, Ahmet, Kandoth, Cyriac, Patel, Ruchi, Huberman, Kety, Smyth, Lillian M., Jhaveri, Komal, Modi, Shanu, Traina, Tiffany A., Dang, Chau, Zhang, Wen, Weigelt, Britta, Li, Bob T., Ladanyi, Marc, Hyman, David M., Schultz, Nikolaus, Robson, Mark E., Hudis, Clifford, Brogi, Edi, Viale, Agnes, Norton, Larry, Dickler, Maura N., Berger, Michael F., Iacobuzio-Donahue, Christine A., Chandarlapaty, Sarat, Scaltriti, Maurizio, Reis-Filho, Jorge S., Solit, David B., Taylor, Barry S., Baselga, José
Опубликовано в: Cancer Cell (2018)

OncoKB: A Precision Oncology Knowledge Base

по Chakravarty, Debyani, Gao, Jianjiong, Phillips, Sarah, Kundra, Ritika, Zhang, Hongxin, Wang, Jiaojiao, Rudolph, Julia E., Yaeger, Rona, Soumerai, Tara, Nissan, Moriah H., Chang, Matthew T., Chandarlapaty, Sarat, Traina, Tiffany A., Paik, Paul K., Ho, Alan L., Hantash, Feras M., Grupe, Andrew, Baxi, Shrujal S., Callahan, Margaret K., Snyder, Alexandra, Chi, Ping, Danila, Daniel C., Gounder, Mrinal, Harding, James J., Hellmann, Matthew D., Iyer, Gopa, Janjigian, Yelena Y., Kaley, Thomas, Levine, Douglas A., Lowery, Maeve, Omuro, Antonio, Postow, Michael A., Rathkopf, Dana, Shoushtari, Alexander N., Shukla, Neerav, Voss, Martin H., Paraiso, Ederlinda, Zehir, Ahmet, Berger, Michael F., Taylor, Barry S., Saltz, Leonard B., Riely, Gregory J., Ladanyi, Marc, Hyman, David M., Baselga, José, Sabbatini, Paul, Solit, David B., Schultz, Nikolaus
Опубликовано в: JCO Precis Oncol (2017)

Oncogenic Signaling Pathways in The Cancer Genome Atlas

по Sanchez-Vega, Francisco, Mina, Marco, Armenia, Joshua, Chatila, Walid K., Luna, Augustin, La, Konnor C., Dimitriadoy, Sofia, Liu, David L., Kantheti, Havish S., Saghafinia, Sadegh, Chakravarty, Debyani, Daian, Foysal, Gao, Qingsong, Bailey, Matthew H., Liang, Wen-Wei, Foltz, Steven M., Shmulevich, Ilya, Ding, Li, Heins, Zachary, Ochoa, Angelica, Gross, Benjamin, Gao, Jianjiong, Zhang, Hongxin, Kundra, Ritika, Kandoth, Cyriac, Bahceci, Istemi, Dervishi, Leonard, Dogrusoz, Ugur, Zhou, Wanding, Shen, Hui, Laird, Peter W., Way, Gregory P., Greene, Casey S., Liang, Han, Xiao, Yonghong, Wang, Chen, Iavarone, Antonio, Berger, Alice H., Bivona, Trever G., Lazar, Alexander J., Hammer, Gary D., Giordano, Thomas, Kwong, Lawrence N., McArthur, Grant, Huang, Chenfei, Tward, Aaron D., Frederick, Mitchell J., McCormick, Frank, Meyerson, Matthew, Van Allen, Eliezer M., Cherniack, Andrew D., Ciriello, Giovanni, Sander, Chris, Schultz, Nikolaus
Опубликовано в: Cell (2018)