Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next-Generation Sequencing for Matching Patients to Targeted and Immune Therapies

PURPOSE: Prior molecular profiling of hepatocellular carcinoma (HCC) has identified actionable findings that may have a role in guiding therapeutic decision-making and clinical trial enrollment. We implemented prospective next-generation sequencing (NGS) in the clinic to determine whether such analy...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Harding, James J., Nandakumar, Subhiksha, Armenia, Joshua, Khalil, Danny N., Albano, Melanie, Ly, Michele, Shia, Jinru, Hechtman, Jaclyn F., Kundra, Ritika, Dika, Imane El, Do, Richard K., Sun, Yichao, Kingham, T. Peter, D’Angelica, Michael I., Berger, Michael F., Hyman, David M., Jarnagin, William, Klimstra, David S, Janjigian, Yelena Y., Solit, David B., Schultz, Nikolaus, Abou-Alfa, Ghassan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689131/
https://ncbi.nlm.nih.gov/pubmed/30373752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2293
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