Comprehensive molecular profiling of intra- and extrahepatic cholangiocarcinomas: potential targets for intervention.

PURPOSE: Various genetic driver aberrations have been identified among distinct anatomic and clinical subtypes of intrahepatic and extrahepatic cholangiocarcinoma, and these molecular alterations may be prognostic biomarkers and/or predictive of drug response. EXPERIMENTAL DESIGN: Tumor samples from...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Lowery, Maeve A., Ptashkin, Ryan, Jordan, Emmet, Berger, Michael F., Zehir, Ahmet, Capanu, Marinela, Kemeny, Nancy E., O’Reilly, Eileen M., El-Dika, Imane, Jarnagin, William R., Harding, James J., D’Angelica, Michael I., Cercek, Andrea, Hechtman, Jaclyn F., Solit, David B., Schultz, Nikolaus, Hyman, David M., Klimstra, David S., Saltz, Leonard B., Abou-Alfa, Ghassan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642361/
https://ncbi.nlm.nih.gov/pubmed/29848569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0078
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