Molecular Profiling and Analysis of Genetic Aberrations Aimed at Identifying Potential Therapeutic Targets in Fibrolamellar Carcinoma of the Liver

BACKGROUND: Fibrolamellar carcinoma (FLC) is a rare primary liver cancer of young adults. A functional chimeric transcript resulting from the in-frame fusion of the DNAJ homolog, subfamily B, member 1 (DNAJB1), and the catalytic subunit of protein kinase A (PRKACA) genes on chromosome 19 is believed...

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Foilsithe in:Cancer
Main Authors: Dika, Imane El, Bowman, Anita S., Berger, Michael F., Capanu, Marinela, Chou, Joanne F., Benayed, Ryma, Zehir, Ahmet, Shia, Jinru, O’Reilly, Eileen M., Klimstra, David S., Solit, David B., Abou-Alfa, Ghassan K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224539/
https://ncbi.nlm.nih.gov/pubmed/32663328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32960
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