Somatic HNF1A Mutations in the Malignant Transformation of Hepatocellular Adenomas: A Retrospective Analysis of Data from MSK-IMPACT and TCGA

Mutations of Hepatocyte-Nuclear-Factor-1-Homeobox-A gene and loss of Liver-Fatty-Acid-Binding-Protein are well documented in hepatocellular adenoma. However, the role of Hepatocyte-NuclearFactor-1-Homeobox-A mutations in hepatocellular carcinoma remains to be determined. In this study, all hepatocel...

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Publicado en:Hum Pathol
Main Authors: Hechtman, Jaclyn F, Alfa, Ghassan K. Abou, Stadler, Zsofia K., Mandelker, Diana L, Roehrl, Michael H.A., Zehir, Ahmet, Vakiani, Efsevia, Middha, Sumit, Klimstra, David S, Shia, Jinru
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365190/
https://ncbi.nlm.nih.gov/pubmed/30121369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humpath.2018.08.004
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