Retained Mismatch Repair Protein Expression Occurs in Approximately 6% of Microsatellite Instability-High Cancers and is Associated with Missense Mutations in Mismatch Repair Genes.

Immunohistochemistry for mismatch repair protein expression is widely used as a surrogate for microsatellite instability status- an important signature for immunotherapy and germline testing. There are no systematic analyses examining the sensitivity of immunohistochemistry for microsatellite instab...

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Detalhes bibliográficos
Publicado no:Mod Pathol
Main Authors: Hechtman, Jaclyn F., Rana, Satshil, Middha, Sumit, Stadler, Zsofia K., Latham, Alicia, Benayed, Ryma, Soslow, Robert, Ladanyi, Marc, Yaeger, Rona, Zehir, Ahmet, Shia, Jinru
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7195218/
https://ncbi.nlm.nih.gov/pubmed/31857677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41379-019-0414-6
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