Characterization and Clinical Outcomes of DNA Mismatch Repair Deficient (MMR-D) Small Bowel Adenocarcinoma

BACKGROUND: The prevalence and clinical characteristics of small bowel adenocarcinomas (SBAs) in the setting of LS have not been well-studied. We characterized SBA according to DNA mismatch repair and/or microsatellite instability (MMR/MSI) and germline mutation status and compared clinical outcomes...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Latham, Alicia, Shia, Jinru, Patel, Zalak, Lagunes, Diane Reidy, Segal, Neil H., Yaeger, Rona, Ganesh, Karuna, Connell, Louise, Kemeny, Nancy, Kelsen, David, Hechtman, Jaclyn, Nash, Garrett, Paty, Philip, Zehir, Ahmet, Tkachuk, Kaitlin A., Sheikh, Rania, Markowitz, Arnold, Mandelker, Diana, Offit, Kenneth, Berger, Michael F., Cercek, Andrea, Aguilar, Julio Garcia, Saltz, Leonard B., Weiser, Martin, Stadler, Zsofia K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925361/
https://ncbi.nlm.nih.gov/pubmed/33199489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-2892
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