Accelerating discovery of functional mutant alleles in cancer

Most mutations in cancer are rare, which complicates the identification of therapeutically significant mutations and thus limits the clinical impact of genomic profiling in cancer patients. Here, we analyzed 24,592 cancers including 10,336 prospectively sequenced patients with advanced disease to id...

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Detaylı Bibliyografya
Yayımlandı:Cancer Discov
Asıl Yazarlar: Chang, Matthew T., Bhattarai, Tripti Shrestha, Schram, Alison M., Bielski, Craig M., Donoghue, Mark T.A., Jonsson, Philip, Chakravarty, Debyani, Phillips, Sarah, Kandoth, Cyriac, Penson, Alexander, Gorelick, Alexander, Shamu, Tambudzai, Patel, Swati, Harris, Christopher, Gao, JianJiong, Sumer, Selcuk Onur, Kundra, Ritika, Razavi, Pedram, Li, Bob T., Reales, Dalicia N., Socci, Nicholas D., Jayakumaran, Gowtham, Zehir, Ahmet, Benayed, Ryma, Arcila, Maria E, Chandarlapaty, Sarat, Ladanyi, Marc, Schultz, Nikolaus, Baselga, Jose, Berger, Michael F., Rosen, Neal, Solit, David B., Hyman, David M., Taylor, Barry S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809279/
https://ncbi.nlm.nih.gov/pubmed/29247016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-0321
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