Accelerating discovery of functional mutant alleles in cancer

Most mutations in cancer are rare, which complicates the identification of therapeutically significant mutations and thus limits the clinical impact of genomic profiling in cancer patients. Here, we analyzed 24,592 cancers including 10,336 prospectively sequenced patients with advanced disease to id...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cancer Discov
Κύριοι συγγραφείς: Chang, Matthew T., Bhattarai, Tripti Shrestha, Schram, Alison M., Bielski, Craig M., Donoghue, Mark T.A., Jonsson, Philip, Chakravarty, Debyani, Phillips, Sarah, Kandoth, Cyriac, Penson, Alexander, Gorelick, Alexander, Shamu, Tambudzai, Patel, Swati, Harris, Christopher, Gao, JianJiong, Sumer, Selcuk Onur, Kundra, Ritika, Razavi, Pedram, Li, Bob T., Reales, Dalicia N., Socci, Nicholas D., Jayakumaran, Gowtham, Zehir, Ahmet, Benayed, Ryma, Arcila, Maria E, Chandarlapaty, Sarat, Ladanyi, Marc, Schultz, Nikolaus, Baselga, Jose, Berger, Michael F., Rosen, Neal, Solit, David B., Hyman, David M., Taylor, Barry S.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2017
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809279/
https://ncbi.nlm.nih.gov/pubmed/29247016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-0321
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