A Performance Comparison of Commonly Used Assays to Detect RET Fusions

PURPOSE: Selpercatinib and pralsetinib induce deep and durable responses in advanced RET fusion-positive lung and thyroid cancer patients. RET fusion testing strategies with rapid and reliable results are critical given recent FDA approval. Here, we assess various clinical assays in a large pan-canc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Cancer Res
Prif Awduron: Yang, Soo-Ryum, Aypar, Umut, Rosen, Ezra Y., Mata, Douglas A., Benayed, Ryma, Mullaney, Kerry, Jayakumaran, Gowtham, Zhang, Yanming, Frosina, Denise, Drilon, Alexander, Ladanyi, Marc, Jungbluth, Achim, Rekhtman, Natasha, Hechtman, Jaclyn F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285056/
https://ncbi.nlm.nih.gov/pubmed/33272981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-3208
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