NTRK Fusions Define a Novel Uterine Sarcoma Subtype with Features of Fibrosarcoma

Tropomyosin receptor kinase (Trk) inhibitors have shown high response rates in patients with tumors harboring NTRK fusions. We identified four NTRK fusion-positive uterine sarcomas that should be distinguished from leiomyosarcoma and undifferentiated uterine sarcoma. NTRK rearrangements were detecte...

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Detalhes bibliográficos
Publicado no:Am J Surg Pathol
Main Authors: Chiang, Sarah, Cotzia, Paolo, Hyman, David M., Drilon, Alexander, Tap, William D., Zhang, Lei, Hechtman, Jaclyn F., Frosina, Denise, Jungbluth, Achim A., Murali, Rajmohan, Park, Kay J., Soslow, Robert A., Oliva, Esther, Iafrate, A. John, Benayed, Ryma, Ladanyi, Marc, Antonescu, Cristina R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764747/
https://ncbi.nlm.nih.gov/pubmed/29553955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000001055
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