Novel PLAG1 Gene Rearrangement Distinguishes a Subset of Uterine Myxoid Leiomyosarcoma from Other Uterine Myxoid Mesenchymal Tumors

Genetic alterations in uterine myxoid leiomyosarcoma are unknown. We investigate the clinicopathologic features of 19 uterine tumors previously diagnosed as myxoid leiomyosarcomas in which tumoral RNA was subjected to targeted RNA sequencing. PLAG1, BCOR, BCORL1, HMGA2, and ALK break-apart fluoresce...

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Detalhes bibliográficos
Publicado no:Am J Surg Pathol
Main Authors: Arias-Stella, Javier A., Benayed, Ryma, Oliva, Esther, Young, Robert H., Hoang, Lien N., Lee, Cheng-Han, Jungbluth, Achim A., Frosina, Denise, Soslow, Robert A., Antonescu, Cristina R., Ladanyi, Marc, Chiang, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764762/
https://ncbi.nlm.nih.gov/pubmed/30489320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000001196
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