Novel PLAG1 Gene Rearrangement Distinguishes a Subset of Uterine Myxoid Leiomyosarcoma from Other Uterine Myxoid Mesenchymal Tumors

Genetic alterations in uterine myxoid leiomyosarcoma are unknown. We investigate the clinicopathologic features of 19 uterine tumors previously diagnosed as myxoid leiomyosarcomas in which tumoral RNA was subjected to targeted RNA sequencing. PLAG1, BCOR, BCORL1, HMGA2, and ALK break-apart fluoresce...

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Détails bibliographiques
Publié dans:Am J Surg Pathol
Auteurs principaux: Arias-Stella, Javier A., Benayed, Ryma, Oliva, Esther, Young, Robert H., Hoang, Lien N., Lee, Cheng-Han, Jungbluth, Achim A., Frosina, Denise, Soslow, Robert A., Antonescu, Cristina R., Ladanyi, Marc, Chiang, Sarah
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764762/
https://ncbi.nlm.nih.gov/pubmed/30489320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000001196
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