NTRK fusion detection across multiple assays and 33,997 cases: diagnostic implications and pitfalls

With the FDA approval of larotrectinib, NTRK fusion assessment has recently become a standard part of management for patients with locally advanced or metastatic cancers. Unlike somatic mutation assessment, the detection of NTRK fusions is not straightforward, and various assays exist at the DNA, RN...

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Detalhes bibliográficos
Publicado no:Mod Pathol
Main Authors: Solomon, James P., Linkov, Irina, Rosado, Andrea, Mullaney, Kerry, Rosen, Ezra Y., Frosina, Denise, Jungbluth, Achim A., Zehir, Ahmet, Benayed, Ryma, Drilon, Alexander, Hyman, David M., Ladanyi, Marc, Sireci, Anthony N., Hechtman, Jaclyn F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7437403/
https://ncbi.nlm.nih.gov/pubmed/31375766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41379-019-0324-7
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