Genetic Determinants of Cisplatin Resistance in Patients With Advanced Germ Cell Tumors

PURPOSE: Owing to its exquisite chemotherapy sensitivity, most patients with metastatic germ cell tumors (GCTs) are cured with cisplatin-based chemotherapy. However, up to 30% of patients with advanced GCT exhibit cisplatin resistance, which requires intensive salvage treatment, and have a 50% risk...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Bagrodia, Aditya, Lee, Byron H., Lee, William, Cha, Eugene K., Sfakianos, John P., Iyer, Gopa, Pietzak, Eugene J., Gao, Sizhi Paul, Zabor, Emily C., Ostrovnaya, Irina, Kaffenberger, Samuel D., Syed, Aijazuddin, Arcila, Maria E., Chaganti, Raju S., Kundra, Ritika, Eng, Jana, Hreiki, Joseph, Vacic, Vladimir, Arora, Kanika, Oschwald, Dayna M., Berger, Michael F., Bajorin, Dean F., Bains, Manjit S., Schultz, Nikolaus, Reuter, Victor E., Sheinfeld, Joel, Bosl, George J., Al-Ahmadie, Hikmat A., Solit, David B., Feldman, Darren R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2016
Assuntos:
ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477828/
https://ncbi.nlm.nih.gov/pubmed/27646943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.68.7798
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