Genetic Determinants of Cisplatin Resistance in Patients With Advanced Germ Cell Tumors

PURPOSE: Owing to its exquisite chemotherapy sensitivity, most patients with metastatic germ cell tumors (GCTs) are cured with cisplatin-based chemotherapy. However, up to 30% of patients with advanced GCT exhibit cisplatin resistance, which requires intensive salvage treatment, and have a 50% risk...

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書誌詳細
出版年:J Clin Oncol
主要な著者: Bagrodia, Aditya, Lee, Byron H., Lee, William, Cha, Eugene K., Sfakianos, John P., Iyer, Gopa, Pietzak, Eugene J., Gao, Sizhi Paul, Zabor, Emily C., Ostrovnaya, Irina, Kaffenberger, Samuel D., Syed, Aijazuddin, Arcila, Maria E., Chaganti, Raju S., Kundra, Ritika, Eng, Jana, Hreiki, Joseph, Vacic, Vladimir, Arora, Kanika, Oschwald, Dayna M., Berger, Michael F., Bajorin, Dean F., Bains, Manjit S., Schultz, Nikolaus, Reuter, Victor E., Sheinfeld, Joel, Bosl, George J., Al-Ahmadie, Hikmat A., Solit, David B., Feldman, Darren R.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Clinical Oncology 2016
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ORIGINAL REPORTS
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477828/
https://ncbi.nlm.nih.gov/pubmed/27646943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.68.7798
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