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Clonal relatedness and mutational differences between upper tract and bladder urothelial carcinoma

PURPOSE: To investigate genomic differences between urothelial carcinomas of the upper tract (UTUC) and bladder (UCB), with a focus on defining the clonal relatedness of temporally distinct tumors. EXPERIMENTAL DESIGN: We prospectively sequenced tumors and matched germline DNA using targeted next-ge...

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Publicado en:Clin Cancer Res
Main Authors: AUDENET, François, ISHARWAL, Sumit, CHA, Eugene K., DONOGHUE, Mark T. A., DRILL, Esther N., OSTROVNAYA, Irina, PIETZAK, Eugene J., SFAKIANOS, John P., BAGRODIA, Aditya, MURUGAN, Paari, DALBAGNI, Guido, DONAHUE, Timothy F., ROSENBERG, Jonathan E., BAJORIN, Dean F., ARCILA, Maria E., HECHTMAN, Jaclyn F., BERGER, Michael F., TAYLOR, Barry S., AL-AHMADIE, Hikmat, IYER, Gopa, BOCHNER, Bernard H., COLEMAN, Jonathan A., SOLIT, David B.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359971/
https://ncbi.nlm.nih.gov/pubmed/30352907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2039
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