Clonal relatedness and mutational differences between upper tract and bladder urothelial carcinoma

PURPOSE: To investigate genomic differences between urothelial carcinomas of the upper tract (UTUC) and bladder (UCB), with a focus on defining the clonal relatedness of temporally distinct tumors. EXPERIMENTAL DESIGN: We prospectively sequenced tumors and matched germline DNA using targeted next-ge...

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Udgivet i:Clin Cancer Res
Main Authors: AUDENET, François, ISHARWAL, Sumit, CHA, Eugene K., DONOGHUE, Mark T. A., DRILL, Esther N., OSTROVNAYA, Irina, PIETZAK, Eugene J., SFAKIANOS, John P., BAGRODIA, Aditya, MURUGAN, Paari, DALBAGNI, Guido, DONAHUE, Timothy F., ROSENBERG, Jonathan E., BAJORIN, Dean F., ARCILA, Maria E., HECHTMAN, Jaclyn F., BERGER, Michael F., TAYLOR, Barry S., AL-AHMADIE, Hikmat, IYER, Gopa, BOCHNER, Bernard H., COLEMAN, Jonathan A., SOLIT, David B.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359971/
https://ncbi.nlm.nih.gov/pubmed/30352907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2039
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