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Clinical and molecular predictors of response to immune checkpoint inhibitors in patients with advanced esophagogastric cancer

PURPOSE: Immune checkpoint inhibitors (ICIs) are effective in only a minority of patients with esophagogastric cancer (EGC). Here, we aimed to identify predictors of durable clinical benefit to ICI in EGC. EXPERIMENTAL DESIGN: Patients with advanced EGC treated with ICIs at Memorial Sloan Kettering...

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Publicat a:Clin Cancer Res
Autors principals: Greally, Megan, Chou, Joanne F., Chatila, Walid K., Margolis, Matthew, Capanu, Marinela, Hechtman, Jaclyn F., Tuvy, Yaelle, Kundra, Ritika, Daian, Foysal, Ladanyi, Marc, Kelsen, David P., Ilson, David H., Berger, Michael F., Tang, Laura H., Solit, David B., Diaz, Luis A., Schultz, Nikolaus, Janjigian, Yelena Y., Ku, Geoffrey Y.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6905384/
https://ncbi.nlm.nih.gov/pubmed/31337644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-3603
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