Identification of Salvia haenkei as gerosuppressant agent by using an integrated senescence-screening assay

by Matic, Ivana, Revandkar, Ajinkya, Chen, Jingjing, Bisio, Angela, Dall'Acqua, Stefano, Cocetta, Veronica, Brun, Paola, Mancino, Giorgio, Milanese, Martina, Mattei, Maurizio, Montopoli, Monica, Alimonti, Andrea
Published in Aging (Albany NY) (2016)

Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence

by Revandkar, Ajinkya, Perciato, Maria Luna, Toso, Alberto, Alajati, Abdullah, Chen, Jingjing, Gerber, Hermeto, Dimitrov, Mitko, Rinaldi, Andrea, Delaleu, Nicolas, Pasquini, Emiliano, D'Antuono, Rocco, Pinton, Sandra, Losa, Marco, Gnetti, Letizia, Arribas, Alberto, Fraering, Patrick, Bertoni, Francesco, Nepveu, Alain, Alimonti, Andrea
Published in Nat Commun (2016)

Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer

by Di Mitri, Diletta, Mirenda, Michela, Vasilevska, Jelena, Calcinotto, Arianna, Delaleu, Nicolas, Revandkar, Ajinkya, Gil, Veronica, Boysen, Gunther, Losa, Marco, Mosole, Simone, Pasquini, Emiliano, D’Antuono, Rocco, Masetti, Michela, Zagato, Elena, Chiorino, Giovanna, Ostano, Paola, Rinaldi, Andrea, Gnetti, Letizia, Graupera, Mariona, Martins Figueiredo Fonseca, Ana Raquel, Pereira Mestre, Ricardo, Waugh, David, Barry, Simon, De Bono, Johann, Alimonti, Andrea
Published in Cell Rep (2019)

Targeting PML in triple negative breast cancer elicits growth suppression and senescence

by Arreal, Leire, Piva, Marco, Fernández, Sonia, Revandkar, Ajinkya, Schaub- Clerigué, Ariane, Villanueva, Josep, Zabala-Letona, Amaia, Pujana, Mikel, Astobiza, Ianire, Cortazar, Ana Rosa, Hermanova, Ivana, Bozal-Basterra, Laura, Arruabarrena-Aristorena, Amaia, Crespo, Jana R., Valcarcel-Jimenez, Lorea, Zúñiga-García, Patricia, Canals, Francesc, Torrano, Veronica, Barrio, Rosa, Sutherland, James D., Alimonti, Andrea, Martin-Martin, Natalia, Carracedo, Arkaitz
Published in Cell Death Differ (2019)

Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer

by Chen, Jingjing, Guccini, Ilaria, Di Mitri, Diletta, Brina, Daniela, Revandkar, Ajinkya, Sarti, Manuela, Pasquini, Emiliano, Alajati, Abdullah, Pinton, Sandra, Losa, Marco, Civenni, Gianluca, Catapano, Carlo V., Sgrignani, Jacopo, Cavalli, Andrea, D'Antuono, Rocco, Asara, John M., Morandi, Andrea, Chiarugi, Paola, Crotti, Sara, Agostini, Marco, Montopoli, Monica, Masgras, Ionica, Rasola, Andrea, Garcia-Escudero, Ramon, Delaleu, Nicolas, Rinaldi, Andrea, Bertoni, Francesco, de Bono, Johann, Carracedo, Arkaitz, Alimonti, Andrea
Published in Nat Genet (2018)

CDCP1 overexpression drives prostate cancer progression and can be targeted in vivo

by Alajati, Abdullah, D’Ambrosio, Mariantonietta, Troiani, Martina, Mosole, Simone, Pellegrini, Laura, Chen, Jingjing, Revandkar, Ajinkya, Bolis, Marco, Theurillat, Jean-Philippe, Guccini, Ilaria, Losa, Marco, Calcinotto, Arianna, De Bernardis, Gaston, Pasquini, Emiliano, D’Antuono, Rocco, Sharp, Adam, Figueiredo, Ines, Nava Rodrigues, Daniel, Welti, Jonathan, Gil, Veronica, Yuan, Wei, Vlajnic, Tatjana, Bubendorf, Lukas, Chiorino, Giovanna, Gnetti, Letizia, Torrano, Verónica, Carracedo, Arkaitz, Camplese, Laura, Hirabayashi, Susumu, Canato, Elena, Pasut, Gianfranco, Montopoli, Monica, Rüschoff, Jan Hendrik, Wild, Peter, Moch, Holger, De Bono, Johann, Alimonti, Andrea
Published in J Clin Invest (2020)

mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

by Zabala-Letona, Amaia, Arruabarrena-Aristorena, Amaia, Martín-Martín, Natalia, Fernandez-Ruiz, Sonia, Sutherland, James D., Clasquin, Michelle, Tomas-Cortazar, Julen, Jimenez, Jose, Torres, Ines, Quang, Phong, Ximenez-Embun, Pilar, Bago, Ruzica, Ugalde-Olano, Aitziber, Loizaga-Iriarte, Ana, Lacasa-Viscasillas, Isabel, Unda, Miguel, Torrano, Verónica, Cabrera, Diana, van Liempd, Sebastiaan M., Cendon, Ylenia, Castro, Elena, Murray, Stuart, Revandkar, Ajinkya, Alimonti, Andrea, Zhang, Yinan, Barnett, Amelia, Lein, Gina, Pirman, David, Cortazar, Ana R., Arreal, Leire, Prudkin, Ludmila, Astobiza, Ianire, Valcarcel-Jimenez, Lorea, Zuñiga-García, Patricia, Fernandez-Dominguez, Itziar, Piva, Marco, Caro-Maldonado, Alfredo, Sánchez-Mosquera, Pilar, Castillo-Martín, Mireia, Serra, Violeta, Beraza, Naiara, Gentilella, Antonio, Thomas, George, Azkargorta, Mikel, Elortza, Felix, Farràs, Rosa, Olmos, David, Efeyan, Alejo, Anguita, Juan, Muñoz, Javier, Falcón-Pérez, Juan M., Barrio, Rosa, Macarulla, Teresa, Mato, Jose M., Martinez-Chantar, Maria L., Cordon-Cardo, Carlos, Aransay, Ana M., Marks, Kevin, Baselga, José, Tabernero, Josep, Nuciforo, Paolo, Manning, Brendan D., Marjon, Katya, Carracedo, Arkaitz
Published in Nature (2017)