Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer

Tumor-associated macrophages (TAMs) represent a major component of the tumor microenvironment supporting tumorigenesis. TAMs re-education has been proposed as a strategy to promote tumor inhibition. However, whether this approach may work in prostate cancer is unknown. Here we find that Pten-null pr...

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Udgivet i:Cell Rep
Main Authors: Di Mitri, Diletta, Mirenda, Michela, Vasilevska, Jelena, Calcinotto, Arianna, Delaleu, Nicolas, Revandkar, Ajinkya, Gil, Veronica, Boysen, Gunther, Losa, Marco, Mosole, Simone, Pasquini, Emiliano, D’Antuono, Rocco, Masetti, Michela, Zagato, Elena, Chiorino, Giovanna, Ostano, Paola, Rinaldi, Andrea, Gnetti, Letizia, Graupera, Mariona, Martins Figueiredo Fonseca, Ana Raquel, Pereira Mestre, Ricardo, Waugh, David, Barry, Simon, De Bono, Johann, Alimonti, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715643/
https://ncbi.nlm.nih.gov/pubmed/31433989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.07.068
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