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FOXA1 mutations influence the therapeutic response of breast cancer by altering chromatin state
Forkhead box protein A1 (FOXA1) is a pioneer transcription factor that contributes to chromatin opening to allow binding of estrogen receptor (ER) in ER+ breast cancer. Mutations in FOXA1 are recurrent in breast cancer but the functional consequences of these mutations remain unknown. We identified...
Gespeichert in:
| Veröffentlicht in: | Mol Cell Oncol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8128199/ https://ncbi.nlm.nih.gov/pubmed/34027035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2021.1891831 |
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