RSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer

The PI3K signaling pathway regulates diverse cellular processes, including proliferation, survival, and metabolism, and is aberrantly activated in human cancer. As such, numerous compounds targeting the PI3K pathway are currently being clinically evaluated for the treatment of cancer, and several ha...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Serra, Violeta, Eichhorn, Pieter J.A., García-García, Celina, Ibrahim, Yasir H., Prudkin, Ludmila, Sánchez, Gertrudis, Rodríguez, Olga, Antón, Pilar, Parra, Josep-Lluís, Marlow, Sara, Scaltriti, Maurizio, Pérez-Garcia, José, Prat, Aleix, Arribas, Joaquín, Hahn, William C., Kim, So Young, Baselga, José
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668839/
https://ncbi.nlm.nih.gov/pubmed/23635776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66343
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky