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RSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer
The PI3K signaling pathway regulates diverse cellular processes, including proliferation, survival, and metabolism, and is aberrantly activated in human cancer. As such, numerous compounds targeting the PI3K pathway are currently being clinically evaluated for the treatment of cancer, and several ha...
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| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668839/ https://ncbi.nlm.nih.gov/pubmed/23635776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66343 |
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