A Structural Guide to Proteins of the NF-κB Signaling Module

gan Huxford, Tom, Ghosh, Gourisankar
Cyhoeddwyd 2009

Transgenic expression and purification of myosin isoforms using the Drosophila melanogaster indirect flight muscle system

gan Caldwell, James T., Melkani, Girish C., Huxford, Tom, Bernstein, Sanford I.
Cyhoeddwyd 2011

Biochemical and structural characterization of lysophosphatidic acid binding by a humanized monoclonal antibody

gan Fleming, Jonathan K., Wojciak, Jonathan M., Campbell, Mary-Ann, Huxford, Tom
Cyhoeddwyd 2011

Genome reading by the NF-κB transcription factors

gan Mulero, Maria Carmen, Wang, Vivien Ya-Fan, Huxford, Tom, Ghosh, Gourisankar
Cyhoeddwyd yn Nucleic Acids Res (2019)

Biophysical characterization of the free IκBα ankyrin repeat domain in solution

gan Croy, Carrie Hughes, Bergqvist, Simon, Huxford, Tom, Ghosh, Gourisankar, Komives, Elizabeth A.
Cyhoeddwyd 2004

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

gan Hansen, Scott B, Sulzenbacher, Gerlind, Huxford, Tom, Marchot, Pascale, Taylor, Palmer, Bourne, Yves
Cyhoeddwyd 2005

X-ray crystallographic and molecular dynamic analyses of Drosophila melanogaster embryonic muscle myosin define domains responsible for isoform-specific properties

gan Caldwell, James T., Mermelstein, Daniel J., Walker, Ross C., Bernstein, Sanford I., Huxford, Tom
Cyhoeddwyd yn J Mol Biol (2019)

Thermodynamics reveal that helix four in the NLS of NF-κB p65 anchors IκBα, forming a very stable complex

gan Bergqvist, Simon, Croy, Carrie H., Kjaergaard, Magnus, Huxford, Tom, Ghosh, Gourisankar, Komives, Elizabeth A.
Cyhoeddwyd 2006

Structural Comparison of Three Crystalline Complexes of a Peptidic Toxin With a Synaptic Acetylcholine Recognition Protein

gan Bourne, Yves, Hansen, Scott B., Sulzenbacher, Gerlind, Talley, Todd T., Huxford, Tom, Taylor, Palmer, Marchot, Pascale
Cyhoeddwyd yn J Mol Neurosci (2006)

High-affinity pan-specific monoclonal antibodies that target cysteinyl leukotrienes and show efficacy in an acute model of colitis

gan King, Ashlee N., Fleming, Jonathan K., Knapik, Stephanie S., Visentin, Barbara, Wojciak, Jonathan M., Huxford, Tom
Cyhoeddwyd yn J Lipid Res (2017)

Structurally plastic NEMO and oligomerization prone IKK2 subunits define the behavior of human IKK2:NEMO complexes in solution

gan Ko, Myung Soo, Biswas, Tapan, Mulero, Maria Carmen, Bobkov, Andrey A., Ghosh, Gourisankar, Huxford, Tom
Cyhoeddwyd yn Biochim Biophys Acta Proteins Proteom (2020)

Probing Kinase Activation and Substrate Specificity with an Engineered Monomeric IKK2

gan Hauenstein, Arthur V., Rogers, W. Eric, Shaul, Jacob D., Huang, De-Bin, Ghosh, Gourisankar, Huxford, Tom
Cyhoeddwyd 2014

The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen

gan Wojciak, Jonathan M., Zhu, Norman, Schuerenberg, Karen T., Moreno, Kelli, Shestowsky, William S., Hiraiwa, Masao, Sabbadini, Roger, Huxford, Tom
Cyhoeddwyd 2009

X-ray crystal structure of the UCS domain-containing UNC-45 myosin chaperone from Drosophila melanogaster

gan Lee, Chi F., Hauenstein, Arthur V., Fleming, Jonathan K., Gasper, William C., Engelke, Valerie, Sankaran, Banumathi, Bernstein, Sanford I., Huxford, Tom
Cyhoeddwyd 2011

Ion Binding Properties of a Naturally Occurring Metalloantibody

gan Farokhi, Elinaz, Fleming, Jonathan K., Erasmus, M. Frank, Ward, Aaron D., Wu, Yunjin, Gutierrez, Maria G., Wojciak, Jonathan M., Huxford, Tom
Cyhoeddwyd yn Antibodies (Basel) (2020)

Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450(BM3) Variants

gan Geronimo, Inacrist, Denning, Catherine A., Rogers, W. Eric, Othman, Thaer, Huxford, Tom, Heidary, David K., Glazer, Edith C., Payne, Christina M.
Cyhoeddwyd yn Biochemistry (2016)

Small molecule binding to Inhibitor of nuclear factor kappa-B kinase subunit beta in an ATP non-competitive manner

gan Napoleon, John V., Singh, Sarbjit, Rana, Sandeep, Bendjennat, Mourad, Kumar, Vikas, Kizhake, Smitha, Palermo, Nicholas Y., Ouellette, Michel M., Huxford, Tom, Natarajan, Amarnath
Cyhoeddwyd yn Chem Commun (Camb) (2021)

Protein Cofactors Are Essential for High-Affinity DNA Binding by the Nuclear Factor κB RelA Subunit

gan Mulero, Maria Carmen, Shahabi, Shandy, Ko, Myung Soo, Schiffer, Jamie M., Huang, De-Bin, Wang, Vivien Ya-Fan, Amaro, Rommie E., Huxford, Tom, Ghosh, Gourisankar
Cyhoeddwyd yn Biochemistry (2018)

A Structural Basis for IκB Kinase 2 Activation Via Oligomerization-Dependent Trans Auto-Phosphorylation

gan Polley, Smarajit, Huang, De-Bin, Hauenstein, Arthur V., Fusco, Amanda J., Zhong, Xiangyang, Vu, Don, Schröfelbauer, Bärbel, Kim, Youngchang, Hoffmann, Alexander, Verma, Inder M., Ghosh, Gourisankar, Huxford, Tom
Cyhoeddwyd 2013