A carregar...

Thermodynamics reveal that helix four in the NLS of NF-κB p65 anchors IκBα, forming a very stable complex

IκBα is an ankyrin repeat protein that inhibits NF-κB transcriptional activity by sequestering NF-κB outside of the nucleus in resting cells. We have characterized the binding thermodynamics and kinetics of the IκBα ankyrin repeat domain to NF-κB(p50/p65) using surface plasmon (SPR) resonance and is...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bergqvist, Simon, Croy, Carrie H., Kjaergaard, Magnus, Huxford, Tom, Ghosh, Gourisankar, Komives, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680085/
https://ncbi.nlm.nih.gov/pubmed/16756995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.05.014
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!