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Biophysical characterization of the free IκBα ankyrin repeat domain in solution
The crystal structure of IκBα in complex with the transcription factor, nuclear factor κ-B (NF-κB) shows six ankyrin repeats, which are all ordered. Electron density was not observed for most of the residues within the PEST sequence, although it is required for high-affinity binding. To characterize...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2279933/ https://ncbi.nlm.nih.gov/pubmed/15215520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04731004 |
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