Binding of NFκB Appears to Twist the Ankyrin Repeat Domain of IκBα

Total internal reflection fluorescence-based single-molecule Förster resonance energy transfer (FRET) measurements were previously carried out on the ankyrin repeat domain (ARD) of IκBα, the temporally regulated inhibitor of canonical NFκB signaling. Under native conditions, most of the IκBα molecul...

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Detalles Bibliográficos
Publicado en:Biophys J
Autores principales: Trelle, Morten Beck, Ramsey, Kristen M., Lee, Taehyung C., Zheng, Weihua, Lamboy, Jorge, Wolynes, Peter G., Deniz, Ashok, Komives, Elizabeth A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2016
Materias:
Protein
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776026/
https://ncbi.nlm.nih.gov/pubmed/26910425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.01.001
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