Binding of NFκB Appears to Twist the Ankyrin Repeat Domain of IκBα

Total internal reflection fluorescence-based single-molecule Förster resonance energy transfer (FRET) measurements were previously carried out on the ankyrin repeat domain (ARD) of IκBα, the temporally regulated inhibitor of canonical NFκB signaling. Under native conditions, most of the IκBα molecul...

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Bibliografski detalji
Izdano u:Biophys J
Glavni autori: Trelle, Morten Beck, Ramsey, Kristen M., Lee, Taehyung C., Zheng, Weihua, Lamboy, Jorge, Wolynes, Peter G., Deniz, Ashok, Komives, Elizabeth A.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2016
Teme:
Protein
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776026/
https://ncbi.nlm.nih.gov/pubmed/26910425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.01.001
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