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Single-Molecule FRET Reveals the Native-State Dynamics of the IκBα Ankyrin Repeat Domain

Previous single-molecule fluorescence resonance energy transfer (smFRET) studies in which the second and sixth ankyrin repeats (ARs) of IκBα were labeled with FRET pairs showed slow fluctuations as if the IκBα AR domain was unfolding in its native state. To systematically probe where these slow dyna...

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Autors principals: Lamboy, Jorge A., Kim, Hajin, Dembinski, Holly, Ha, Taekjip, Komives, Elizabeth A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758917/
https://ncbi.nlm.nih.gov/pubmed/23619335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.04.015
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