Visualization of the nanospring dynamics of the IκBα ankyrin repeat domain in real time

IκBα is a crucial regulator of NFκB transcription. NFκB-mediated gene activation is robust because levels of free IκBα are kept extremely low by rapid, ubiquitin-independent degradation of newly synthesized IκBα. IκBα has a weakly folded ankyrin repeat 5–6 (AR5–6) region that is critical in establis...

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Detaylı Bibliyografya
Asıl Yazarlar: Lamboy, Jorge A., Kim, Hajin, Lee, Kyung Suk, Ha, Taekjip, Komives, Elizabeth A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2011
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121830/
https://ncbi.nlm.nih.gov/pubmed/21628581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102226108
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