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Folding Kinetics of the Cooperatively Folded Subdomain of the IκBα Ankyrin Repeat Domain

The ankyrin repeat domain of IκBα consists of a cooperative folding unit of roughly four ankyrin repeats (AR1-4) and of two weakly-folded repeats (ARs5-6). The kinetic folding mechanism of the cooperative subdomain, IκBα(67-206), was analyzed using rapid mixing techniques. Despite its apparent archi...

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Detalhes bibliográficos
Main Authors: DeVries, Ingrid, Ferreiro, Diego U., Sánchez, Ignacio E., Komives, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081522/
https://ncbi.nlm.nih.gov/pubmed/21329696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.02.021
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