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Folding landscapes of ankyrin repeat proteins: experiments meet theory

Nearly 6% of eukaryotic protein sequences contain ankyrin repeat (AR) domains, which consist of several repeats and often function in binding. AR proteins show highly cooperative folding despite a lack of long-range contacts. Both theory and experiment converge to explain that formation of the inter...

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Hlavní autoři: Barrick, Doug, Ferreiro, Diego U., Komives, Elizabeth A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680087/
https://ncbi.nlm.nih.gov/pubmed/18243686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2007.12.004
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