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Folding landscapes of ankyrin repeat proteins: experiments meet theory
Nearly 6% of eukaryotic protein sequences contain ankyrin repeat (AR) domains, which consist of several repeats and often function in binding. AR proteins show highly cooperative folding despite a lack of long-range contacts. Both theory and experiment converge to explain that formation of the inter...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680087/ https://ncbi.nlm.nih.gov/pubmed/18243686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2007.12.004 |
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