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Transfer of Flexibility between Ankyrin Repeats in IκBα upon Formation of the NF-κB Complex

The mechanism of inhibition of the transcriptional activator nuclear factor-kappaB (NF-κB) by the inhibitor IκBα is central to the understanding of the control of transcriptional activity via this widely-employed pathway. Previous studies suggested that IκBα, a modular protein with an NF-κB binding...

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Detalhes bibliográficos
Main Authors: Sue, Shih-Che, Cervantes, Carla, Komives, Elizabeth A., Dyson, H. Jane
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603615/
https://ncbi.nlm.nih.gov/pubmed/18565540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.05.048
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