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Molecular stripping in the NF-κB/IκB/DNA genetic regulatory network

Genetic switches based on the [Formula: see text] system are master regulators of an array of cellular responses. Recent kinetic experiments have shown that [Formula: see text] can actively remove NF-κB bound to its genetic sites via a process called “molecular stripping.” This allows the [Formula:...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Potoyan, Davit A., Zheng, Weihua, Komives, Elizabeth A., Wolynes, Peter G.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711861/
https://ncbi.nlm.nih.gov/pubmed/26699500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520483112
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