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A Structural Guide to Proteins of the NF-κB Signaling Module

The prosurvival transcription factor NF-κB specifically binds promoter DNA to activate target gene expression. NF-κB is regulated through interactions with IκB inhibitor proteins. Active proteolysis of these IκB proteins is, in turn, under the control of the IκB kinase complex (IKK). Together, these...

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Hlavní autoři: Huxford, Tom, Ghosh, Gourisankar
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773632/
https://ncbi.nlm.nih.gov/pubmed/20066103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a000075
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