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A fourth IκB protein within the NF-κB signaling module
Inflammatory NF-κB/RelA activation is mediated by the three canonical inhibitors, IκBα, -β, and -ε. We report here that nfκb2/p100 forms two distinct inhibitory complexes with RelA, one of which mediates developmental NF-κB activation. Our genetic evidence confirms that p100 is required and sufficie...
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| Glavni autori: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1831796/ https://ncbi.nlm.nih.gov/pubmed/17254973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.12.033 |
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