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IκBβ enhances the generation of the low-affinity NFκB/RelA homodimer

The NFκB family of dimeric transcription factors regulate inflammatory and immune responses. While the dynamic control of NFκB dimer activity via the IκB-NFκB signaling module is well understood, there is little information on how specific dimer repertoires are generated from Rel family polypeptides...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Tsui, Rachel, Kearns, Jeffrey D., Lynch, Candace, Vu, Don, Ngo, Kim, Basak, Soumen, Ghosh, Gourisankar, Hoffmann, Alexander
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425231/
https://ncbi.nlm.nih.gov/pubmed/25946967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8068
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