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Substrate complex competition is a regulatory motif that allows NFκB RelA to license but not amplify NFκB RelB
Signaling pathways often share molecular components, tying the activity of one pathway to the functioning of another. In the NFκB signaling system, distinct kinases mediate inflammatory and developmental signaling via RelA and RelB, respectively. Although the substrates of the developmental, so-call...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6535030/ https://ncbi.nlm.nih.gov/pubmed/31048505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816000116 |
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