NF-κB RelA Phosphorylation Regulates RelA Acetylation

The nuclear functions of NF-κB p50/RelA heterodimers are regulated in part by posttranslational modifications of its RelA subunit, including phosphorylation and acetylation. Acetylation at lysines 218, 221, and 310 differentially regulates RelA's DNA binding activity, assembly with IκBα, and tr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Lin-Feng, Williams, Samuel A., Mu, Yajun, Nakano, Hiroyasu, Duerr, James M., Buckbinder, Leonard, Greene, Warner C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234328/
https://ncbi.nlm.nih.gov/pubmed/16135789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.18.7966-7975.2005
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