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Functional Interplay between Acetylation and Methylation of the RelA Subunit of NF-κB

Posttranslational modifications of the RelA subunit of NF-κB, including acetylation and methylation, play a key role in controlling the strength and duration of its nuclear activity. Whether these modifications are functionally linked is largely unknown. Here, we show that the acetylation of lysine...

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Detalhes bibliográficos
Main Authors: Yang, Xiao-Dong, Tajkhorshid, Emad, Chen, Lin-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863596/
https://ncbi.nlm.nih.gov/pubmed/20160011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01343-09
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