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Negative regulation of NF-κB action by Set9-mediated lysine methylation of the RelA subunit
Proper regulation of NF-κB activity is critical to maintain and balance the inflammatory response. Inactivation of the NF-κB complex relies in part on the proteasome-mediated degradation of promoter-bound NF-κB, but the detailed molecular mechanism initiating this process remains elusive. Here, we s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683704/ https://ncbi.nlm.nih.gov/pubmed/19262565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.55 |
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