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Thr(435) phosphorylation regulates RelA (p65) NF-κB subunit transactivation

Phosphorylation of the RelA (p65) NF-κB (nuclear factor κB) subunit has been previously shown to modulate its ability to induce or repress transcription. In the present study we have investigated the consequences of Thr(435) phosphorylation within the C-terminal transactivation domain of RelA. We co...

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Detalhes bibliográficos
Main Authors: O'Shea, John M., Perkins, Neil D.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829238/
https://ncbi.nlm.nih.gov/pubmed/20001970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091630
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