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Regulation of RelA (p65) Function by the Large Subunit of Replication Factor C

The RelA (p65) subunit of NF-κB is an important regulator of inflammation, proliferation, and apoptosis. We have discovered that the large subunit, p140, of replication factor C (RFC) can function as a regulator of RelA. RFC is a clamp loader, facilitating the addition and removal of proliferating-c...

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Detalhes bibliográficos
Main Authors: Anderson, Lisa A., Perkins, Neil D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151544/
https://ncbi.nlm.nih.gov/pubmed/12509469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.2.721-732.2003
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