Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: therapeutic potential of HDAC inhibitors

Clinical management of abdominal aortic aneurysm (AAA) is currently limited to elective surgical repair because an effective pharmacotherapy is still awaited. Inhibition of histone deacetylase (HDAC) activity could be a promising therapeutic option in cardiovascular diseases. We aimed to characteris...

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Detalhes bibliográficos

Principais autores:	María Galán, Saray Varona, Mar Orriols, José Antonio Rodríguez, Silvia Aguiló, Jaume Dilmé, Mercedes Camacho, José Martínez-González, Cristina Rodriguez
Formato:	Artigo
Idioma:	Inglês
Publicado em:	The Company of Biologists 2016-05-01
coleção:	Disease Models & Mechanisms
Assuntos:	Abdominal aortic aneurysm Histone deacetylases Inflammation Vascular remodelling Metalloproteinases
Acesso em linha:	http://dmm.biologists.org/content/9/5/541
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