B-cell survival and development controlled by the coordination of NF-κB family members RelB and cRel

Targeted deletion of BAFF causes severe deficiency of splenic B cells. BAFF-R is commonly thought to signal to nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB)–inducing kinase dependent noncanonical NF-κB RelB. However, RelB-deficient mice have normal B-cell numbers. Recent studies...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood
Main Authors: Almaden, Jonathan V., Liu, Yi C., Yang, Edward, Otero, Dennis C., Birnbaum, Harry, Davis-Turak, Jeremy, Asagiri, Masataka, David, Michael, Goldrath, Ananda W., Hoffmann, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786837/
https://ncbi.nlm.nih.gov/pubmed/26773039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-606988
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados