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Control of RelB during dendritic cell activation integrates canonical and non-canonical NF-κB pathways
The NF-κB protein RelB controls dendritic cell (DC) maturation and may be targeted therapeutically to manipulate T cell responses in disease. Here we report that RelB promoted DC activation not as the expected RelB-p52 effector of the non-canonical NF-κB pathway, but as a RelB-p50 dimer regulated by...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3634611/ https://ncbi.nlm.nih.gov/pubmed/23086447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2446 |
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