Control of RelB during dendritic cell activation integrates canonical and non-canonical NF-κB pathways

The NF-κB protein RelB controls dendritic cell (DC) maturation and may be targeted therapeutically to manipulate T cell responses in disease. Here we report that RelB promoted DC activation not as the expected RelB-p52 effector of the non-canonical NF-κB pathway, but as a RelB-p50 dimer regulated by...

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Autori principali: Shih, Vincent F.-S., Davis-Turak, Jeremy, Macal, Monica, Huang, Jenny Q., Ponomarenko, Julia, Kearns, Jeffrey D., Yu, Tony, Fagerlund, Riku, Asagiri, Masataka, Zuniga, Elina I., Hoffmann, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634611/
https://ncbi.nlm.nih.gov/pubmed/23086447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2446
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