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X-ray crystallographic and molecular dynamic analyses of Drosophila melanogaster embryonic muscle myosin define domains responsible for isoform-specific properties

Drosophila melanogaster is a powerful system for characterizing alternative myosin isoforms and modeling muscle diseases, but high-resolution structures of fruit fly contractile proteins have not been determined. Here we report the first x-ray crystal structure of an insect myosin: the D. melanogast...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Caldwell, James T., Mermelstein, Daniel J., Walker, Ross C., Bernstein, Sanford I., Huxford, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995774/
https://ncbi.nlm.nih.gov/pubmed/31786266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.11.013
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