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Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450(BM3) Variants

Cytochrome P450(BM3) is a heme-containing enzyme from Bacillus megaterium that exhibits high monooxygenase activity and has a self-sufficient electron transfer system in the full-length enzyme. Its potential synthetic applications drive protein engineering efforts to produce variants capable of oxid...

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Dettagli Bibliografici
Pubblicato in:Biochemistry
Autori principali: Geronimo, Inacrist, Denning, Catherine A., Rogers, W. Eric, Othman, Thaer, Huxford, Tom, Heidary, David K., Glazer, Edith C., Payne, Christina M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422958/
https://ncbi.nlm.nih.gov/pubmed/27267136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00183
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