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Substrate Binding to Cytochromes P450

P450s have attracted tremendous attention due not only to their involvement in the metabolism of drug molecules and endogenous substrates but also the unusual nature of the reaction they catalyze, namely the oxidation of unactivated C-H bonds. The binding of substrates to P450s, which is usually vie...

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Publicat a:Anal Bioanal Chem
Autors principals: Isin, Emre M., Guengerich, F. Peter
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756639/
https://ncbi.nlm.nih.gov/pubmed/18622598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-008-2244-0
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