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Substrate Binding to Cytochromes P450

P450s have attracted tremendous attention due not only to their involvement in the metabolism of drug molecules and endogenous substrates but also the unusual nature of the reaction they catalyze, namely the oxidation of unactivated C-H bonds. The binding of substrates to P450s, which is usually vie...

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Detalles Bibliográficos
Publicado en:Anal Bioanal Chem
Main Authors: Isin, Emre M., Guengerich, F. Peter
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756639/
https://ncbi.nlm.nih.gov/pubmed/18622598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-008-2244-0
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