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Substrate Binding to Cytochromes P450

P450s have attracted tremendous attention due not only to their involvement in the metabolism of drug molecules and endogenous substrates but also the unusual nature of the reaction they catalyze, namely the oxidation of unactivated C-H bonds. The binding of substrates to P450s, which is usually vie...

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Bibliografiske detaljer
Udgivet i:Anal Bioanal Chem
Main Authors: Isin, Emre M., Guengerich, F. Peter
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756639/
https://ncbi.nlm.nih.gov/pubmed/18622598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-008-2244-0
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