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Substrate Binding to Cytochromes P450

P450s have attracted tremendous attention due not only to their involvement in the metabolism of drug molecules and endogenous substrates but also the unusual nature of the reaction they catalyze, namely the oxidation of unactivated C-H bonds. The binding of substrates to P450s, which is usually vie...

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Библиографические подробности
Опубликовано в: :Anal Bioanal Chem
Главные авторы: Isin, Emre M., Guengerich, F. Peter
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756639/
https://ncbi.nlm.nih.gov/pubmed/18622598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-008-2244-0
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