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Kinetic Evidence for an Induced Fit Mechanism in the Binding of the Substrate Camphor by Cytochrome P450(cam)
Bacterial cytochrome P450 (P450) 101A1 (P450(cam)) has served as a prototype among the P450 enzymes and has high catalytic activity towards its cognate substrate, camphor. X-ray crystallography and NMR and IR spectroscopy have demonstrated the existence of multiple conformations of many P450s, inclu...
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| Izdano u: | ACS Catal |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8318206/ https://ncbi.nlm.nih.gov/pubmed/34327042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.0c04455 |
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