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Kinetic Evidence for an Induced Fit Mechanism in the Binding of the Substrate Camphor by Cytochrome P450(cam)

Bacterial cytochrome P450 (P450) 101A1 (P450(cam)) has served as a prototype among the P450 enzymes and has high catalytic activity towards its cognate substrate, camphor. X-ray crystallography and NMR and IR spectroscopy have demonstrated the existence of multiple conformations of many P450s, inclu...

詳細記述

保存先:
書誌詳細
出版年:ACS Catal
主要な著者: Guengerich, F. Peter, Child, Stella A., Barckhausen, Ian R., Goldfarb, Margo H.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318206/
https://ncbi.nlm.nih.gov/pubmed/34327042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.0c04455
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