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Substrate binding induces structural changes in cytochrome P450cam
The binding of (+)-camphor to cytochrome P450cam (P450cam) expels a cluster of waters at the active site, raising the redox potential of the haem to an extent that allows reduction by the electron-transfer system. This binding was reported to involve no significant structural changes in the protein....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2635880/ https://ncbi.nlm.nih.gov/pubmed/19193991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108044114 |
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