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Substrate binding induces structural changes in cytochrome P450cam

The binding of (+)-camphor to cytochrome P450cam (P450cam) expels a cluster of waters at the active site, raising the redox potential of the haem to an extent that allows reduction by the electron-transfer system. This binding was reported to involve no significant structural changes in the protein....

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Detaylı Bibliyografya
Asıl Yazarlar: Sakurai, Keisuke, Shimada, Hideo, Hayashi, Takashi, Tsukihara, Tomitake
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: International Union of Crystallography 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635880/
https://ncbi.nlm.nih.gov/pubmed/19193991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108044114
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